ASTRAGALOSIDE IV: AN EFFECTIVE DRUG FOR THE TREATMENT OF CARDIOVASCULAR DISEASES


Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Sickle cell disease (SCD) is caused by a single-point mutation, and the ensuing deoxygenation-induced polymerization of sickle hemoglobin (HbS), and reduction in bioavailability of vascular nitric oxide (NO), contribute to the pathogenesis of the disease.In a proof-of-concept study, we successfully incorporated nitrate ester groups onto two previou

read more

Pneumonia due to Staphylococcus aureus in a diabetic patient

Community-acquired pneumonia is a very common respiratory tract infection, especially in older adults; however, its mortality in outpatients is very low compared to other pathologies.As in other respiratory infections, the etiology includes viruses, bacteria and other microorganisms.The most common bacterial etiology is: Streptococcus d2 gul pneumo

read more